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Spravato spray also known as Esketamine on trials has shown positive results in treating major depressive disorder and treatment-resistant depression. Unlike traditional antidepressants which can take weeks to provide full therapeutic effects, spravato can provide relief within 2 to 24 hours. Spravato can also help reduce suicidal ideations within 24 hours of use.
“One thing almost all psychiatrists can agree on,” psychiatry researcher Adam Kaplin said, “is this: We need antidepressants that work more quickly and for more people.” Esketamine meets that need. “Unlike other antidepressants, esketamine targets dozens of brain connections at once,” he continued.
Recent research suggests that spravato therapy may also be able to help treat other mental health conditions such as:
Data from a 2020 study showed that esketamine pain therapy can help improve psychological distress caused by anxiety and depression. In the study, people with serious illnesses were given 45 minutes of esketamine infusion on a consistent basis to relieve refractory pain. The individuals given esketamine experienced significantly less anxiety despite being in palliative care. The study, though small, concluded that even a single administration of esketamine may help improve the psychological distress experienced by patients with life-threatening conditions. By helping to ease agony, esketamine can also help reduce the risk of co-occurring mental health disorders for people living with terminal illnesses.